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Octopuses adjust to cold by editing their RNA

Octopuses adjust to cold by editing their RNA

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Innovative research reveals how octopuses adapt to frigid waters by editing their RNA, a finding that could have broad implications for biology and biotechnology.

Through RNA editing, the cephalopods appear to have found a unique way of tweaking their own physiology to adapt to environmental temperature changes

A recent study has unveiled a fascinating aspect of octopus biology: their ability to adapt to cold ocean temperatures by making precise edits to their RNA. 

RNA editing is a molecular process through which cells can modify nucleotide sequences in RNA, resulting in proteins that differ from those directly encoded by DNA. This ability is particularly enhanced in octopuses, who use it to fine-tune the functions of their nervous system at low temperatures.

Cold-water adaptation

The study focused on the adaptations of octopuses that inhabit drastically varying thermal environments. Researchers found that cold-water octopuses have developed the capacity to edit their RNA to an extent much more significant than their warm-water counterparts. This editing primarily affects proteins involved in nerve cell function, crucial for maintaining agility and coordination in cold waters.

Importance

This discovery not only deepens our understanding of octopus biology but also opens new avenues for biotechnological applications. By studying these mechanisms, scientists may develop methods to enhance cold tolerance in other organisms, potentially leading to breakthroughs in agriculture and medicine, particularly in enhancing the cold resistance of crops or creating new treatments for neurological disorders.

Sources
Cell (Journal)
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